Mnova NMR has broadened its horizons with novel support for 3D NMR datasets, starting with Bruker-processed files (e.g., 3rrr format). We are actively expanding our capabilities to include time-domain data, expecting to offer this enhancement shortly.

Moreover, our updated version ensures seamless integration with peak lists from NMR software such as CARA, CCPN, Sparky and TopSpin, facilitating a smoother workflow for researchers.

AI-Powered Peak Picking Algorithm

In collaboration with Bruker, we introduce a new peak-picking algorithm for Mnova NMR, powered by Deep Learning. This advanced tool builds on our GSD (Global Spectral Deconvolution) algorithm, enhancing precision in quantitative NMR (qNMR). Together with an AI-enabled automatic baseline and phase correction, it sets a new benchmark for accuracy and efficiency in NMR spectral analysis.

The figure shows a complete deconvolution of a 1H-NMR spectrum using this deep learning-based algorithm, demonstrating exceptional performance.

Mnova NMR now supports 3D NMR datasets, starting with Bruker-processed files (e.g., 3rrr format). We are also expanding to include time-domain data, with this enhancement coming soon. Additionally, our updated version integrates seamlessly with peak lists from NMR software like CARA, CCPN, Sparky, and TopSpin, streamlining workflows for researchers.

The figure shows the new 3D viewer, which displays pseudo 2D NMR experiments, traditional stacked spectra, 2D spectra, and 3D NMR peaks.

Mnova 15 brings significant enhancements to the DOSY module, refining algorithms for more precise spectra computation and incorporating improved error analysis, Weighted, and Monte Carlo fitting. It also expands support for a broader range of PFG experiments.

A new graphical feature has been added to offer clearer and more detailed visual analysis of results.

The figure shows the new DOSY Peaks panel, providing an extensive analysis of diffusion values with interactive plots.

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The Mnova NMR plugin provides the fastest route from FID to a fully processed spectrum, perfect for both non-experts and experienced users. Beginners benefit from its easy-to-use interface that delivers quick, high-quality results with minimal effort, while experts can take advantage of its advanced processing features.

Simply drag and drop your 1D and 2D data from any NMR vendor for instant auto-processing and analysis.

NMR analysis made easier and faster for everyone!

Access a wide range of options, including apodization methods, zero filling, forward and backward linear prediction, various phase and baseline correction algorithms, covariance, symmetrization, diagonalization, binning, normalization, noise reduction, and smoothing techniques.

The automatic analysis uses Global Deconvolution (GSD) to separate all signals in the spectrum.

This fully automated process quickly gets you to your desired analysis point, with full interactive control available at every step if you want to optimize further.

Mnova is a versatile, multi-platform software compatible with Microsoft, macOS, and Linux, with no hardware constraints.

Mnova NMR is vendor-agnostic, designed for heterogeneous environments, and supports datasets from major NMR spectrometer vendors like Bruker, Varian, Jeol, Magritek, Oxford Instruments, Nanalysis, and more.

Check out the full list of supported vendors and NMR file formats. For any questions regarding your datasets format compatibility contact us!

It combines spectra, structure, and assignment tables in one interface, creating an efficient environment for peak assignment across multiple spectra.

Easily assign spectra manually by linking multiplets to atoms, with support from the ‘Assisted Assignment Mode’ tool. Or, use the automatic mode with the Auto Assignment Algorithm, which integrates various software techniques.

The GSD deconvolution tool helps resolve peak overlaps and classify peaks.

The Mnova NMR Graphical User Interface lets you interact with multiple 1D and 2D NMR spectra quickly and easily, offering various visualization, handling, and analysis modes.

Mnova NMR simplifies numerous NMR applications, including:

• Stacking and superimposing multiple 1D or 2D spectra
• Processing, peak picking, and integration of multiple spectra at once
• Fitting curves to peak properties for related spectra (e.g., reaction monitoring, relaxation studies, DOSY processing)

The “Data Analysis” feature enables detailed analysis of 1D NMR experiments, handling multiple series like resonance decay or peak shifts during titration. Easily extract peak intensities and integrals in tabular form and visualize data graphically.

This tool supports applications such as diffusion and relaxation (T1/T2) studies, kinetics, reaction monitoring, and titrations. The figure shows a curve fitted with either a pre-defined equation or one of your choosing.

Mnova NMR features two multivariate analysis tools—binning and PCA—available with separate licenses. Access the Chemometrics module under the Advanced menu with steps for matrix generation, pre-processing, and PCA.

The PCA tool enables easy interaction with PCA plots and spectra, helping beginners learn multivariate analysis.

Mnova NMR also offers two plugins, Advanced Chemometrics and BioHOS,, with separate licenses. The figure shows a color-coded stacked plot identifying key peaks.