“This software easily multiplied our productivity by 3, greatly enhancing the reproducibility and drastically reducing the chance of human error”

Roberto Martinez

Senior Scientist – Novartis

QC Profiling

Benefits

• Efficient evaluation of hundreds of DNA conjugate reactions without throughput limits.​

• Enhanced accuracy with automated deconvolution of peaks and precise mass attribution ensuring error-free results.​

• Consistent interpretation of the results minimizing variability between analyses and reducing mental workload.

• Streamlined analyses enabling quick decision-making based on comprehensive data insights.​

QC Profiling

Features

Flexible Input and Output Configuration

• Flexible Input: Seamlessly incorporate and customize your input using a CSV file. Add and organize inputs into groups to generate comprehensive results for each group, ensuring efficient and structured data processing.
• Customizable Output: Use default templates for reporting or create a unique layout. Customize the CSV output by including specific columns needed for comprehensive reporting, tailoring it to your requirements for improved data analysis and interpretation.

Robust and Customizable Analysis Algorithms

• Streamlined Spectral Deconvolution: Efficiently deconvolute spectra and match primary components of UV peaks for accurate analysis.
• Noisy Chromatogram Identification: Quickly identify and label noisy chromatograms for easy review and further action.
• Accurate Purity Calculations: Exclude residual chromatogram peaks from purity calculations and identify UV peaks from low molecular weight impurities for precise results.

Quality Control tests

• Precise QC Criteria: Define your quality control criteria with specific thresholds and associate distinct flag colors to each criterion. This setup ensures prompt flag generation when a quality test falls short, allowing for immediate issue identification.
• Efficient Review Process: Facilitate a swift and efficient review of results to enhance productivity. The intuitive flagging system enables quick identification and assessment of quality control issues, streamlining the process of addressing and resolving discrepancies. This method improves laboratory productivity and ensures accurate and reliable results.

Streamlined Result Review and Reporting

• Effortless Review: Easily review your analysis results within the Mnova interface. With Mgears and the QC Profiling Result Viewers, access and assess all critical results on a single screen.
• Visual Results: Visualize results with colored charts and instantly spot control flags and warnings for efficient exception-based review.
• Comment and Save: Append comments to your results and save them directly to the output CSV file.
• On-the-Fly Modifications: Modify your analysis by adding or removing masses as you review the results, and launch recalculations as needed.

Latest QC Profiling news

MSChrom supported formats

December 13, 2022

This is the list of provider data sorted per OS supported by Mnova MSChrom. Note that Mnova 15 does not support Windows x32 formats.

Read more

Webinar on Mnova QC Profiling (batch mode)

Wednesday May 5, 2021 12:00 AM

In this webinar you will get some insights on how Mgears and the QC profiling plugin can facilitate the interpretation of up to thousands of LC-MS per week and the subsequent loading of the retrieved information into databases.

Read more

Help & Resources

Guides

QC Profiling - User Manual Mnova Gears - Manual

Videos

Webinar: Semi-automated LC-MS interpretation of DNA conjugates in 96 or 384 well plates

QC Profiling

Related Applications

Identification & Quantification

Academic, Government & Industrial

Target Audience

Organic Chemists

Medicinal Chemists

Analytical Chemists

QC Experts

Other Mnova Solutions

Related Products

Mnova Core

MSChrom

Process, analyze and report your LC-MS and GC-MS data from your different instruments.

Mnova plugin

Mnova Gears

Build automation workflows for your analytical data & more